Which cancers benefit most from NGS testing?

NGS testing is especially valuable in cancers with many actionable targets or complex biology, including lung, breast, colorectal, ovarian, prostate, and pancreatic cancers, melanoma, and gastrointestinal tumors. It’s also important in cancers of unknown primary, rare tumors, and advanced or treatment-resistant disease, where broad molecular profiling can reveal options that standard testing misses.