Analytical Validation and Clinical Implementation of a 1080-Gene Comprehensive Genomic Profiling Assay with Integrated Cloud-Based Analysis for Solid Tumor Molecular Oncology
The Problem With Small Panels Precision oncology depends on knowing the full genomic landscape of a patient’s tumour. Yet most clinical laboratories continue to rely on gene panels covering only 50 to 100 genes– panels that routinely miss critical hotspots, emerging driver mutations, and pan-tumour...
Potential of urine liquid biopsy in detecting of clinically relevant genomic alterations in advanced genitourinary cancers.
When Plasma Can’t Find It; Urine Can Plasma-based liquid biopsy has transformed how we detect and monitor cancer genomically. But it has a quiet blind spot: in patients with low circulating tumour DNA burden, clonal evolution, or treatment-related suppression of ctDNA shedding, plasma...
Single-Cell Circulating Tumor Cell Genomics Reveals KRAS-Independent Oncogenic Sub-Populations and Longitudinal Clonal Evolution in Metastatic Pancreatic Adenocarcinoma
Pancreatic Cancer’s Moving Target:- Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal cancers and one of the hardest to treat precisely, because it doesn’t stay still. PDAC tumours exhibit profound intratumoral heterogeneity, with multiple genetically distinct cell populations evolving rapidly under treatment pressure. Conventional tissue...