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A Novel Liquid Biopsy for Longitudinal Cancer Monitoring and MRD Detection

OncoMonitor® is an advanced blood-based solution designed for real-time monitoring of treatment response, emergence of resistance, and longitudinal tracking of disease progression. By measuring CTCs and ctDNA levels over time, OncoMonitor® provides actionable insights to guide therapy adjustments and detect disease relapse earlier.

Stay Ahead of Cancer Progression

Cancer is dynamic, and timely monitoring is critical for better outcomes.

OncoMonitor® enables oncologists to track disease activity and residual disease in real time — allowing early interventions before clinical relapse becomes visible.

  • OncoMonitor® TRM: Treatment Response Monitoring and Resistance Tracking

  • OncoMonitor® MRD: Minimal Residual Disease Detection after therapy

Longitudinal tracking of disease dynamics using blood-based biomarkers

Real-time assessment of treatment efficacy and emerging resistance

Early detection of minimal residual disease (MRD)

Supports prognosis prediction based on CTC and ctDNA trends

AI-powered reporting for rapid, comprehensive insights

How It Works

1) CTC and ctDNA Quantification

Measures circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) levels from plasma samples.

2 ) Longitudinal Monitoring

Regular blood draws allow dynamic assessment of disease burden, therapy response, and relapse risk over time.

3) Minimal Residual Disease Detection

Trace amounts of ctDNA and CTCs post-treatment signal the presence of residual disease before clinical or radiological signs.

4) Real-Time AI Reporting

Swift, accurate, and dynamic reports generated through the iCARE™ AI-powered analysis platform.

Applications

For Clinicians & Oncologists

  • Monitor cancer patients throughout their treatment journey

  • Adjust therapies based on molecular response or resistance markers

  • Detect relapse earlier than conventional imaging

For Patients Seeking Personalized Therapy

  • Minimize invasive procedures with blood-based monitoring

  • Gain earlier, actionable insights for personalized care adjustments

Why Choose OncoMonitor

  • Covers both early stage and advanced metastatic disease monitoring

  • Enables treatment efficacy assessment through longitudinal CTC/ctDNA tracking

  • Identifies resistance mechanisms and molecular relapse signals

  • AI-driven, real-time reporting enhances decision-making speed and accuracy

Key Actionable Genes Covered (OncoMonitor® TRM)

Cancer TypeKey Genes
LungEGFR, KRAS, MET, ALK, ROS1, RET, TP53, PIK3CA, HRAS, FGFR1/2/3, ERBB2, NRAS, NTRK1/2/3, MAP2K1, PTEN
BreastBRCA1, BRCA2, HER2 (ERBB2), PIK3CA, ESR1, PALB2, TP53, FGFR1/2/3
ColorectalKRAS, NRAS, BRAF, TP53, SMAD4, MLH1, MSH2, MSH6, PMS2, PIK3CA, MET
MelanomaBRAF, NRAS, KIT, PDGFRA, CTNNB1, HRAS, PIK3CA
GastrointestinalKRAS, BRAF, PDGFRA, KIT, MET, SMAD4, MLH1, MSH2, NTRK1/2/3, TP53
OvaryBRCA1, BRCA2, PALB2, BRAF, KRAS, NRAS, TP53
BladderTP53, TSC1, MLH1, MSH2, MSH6, PMS2, NTRK1/2/3

Test Performance Characteristics

  
Sensitivity90.5%
Specificity97.2%
Positive Predictive Value (PPV)95%
Negative Predictive Value (NPV)94.6%
Concordance94.7%
Limit of Detection (LOD)0.05

Is OncoHRD® Clinically Relevant for Your Patients?

  
Longitudinal MonitoringAssess disease burden dynamically over time
Minimal Residual Disease DetectionIdentify occult disease post-therapy
Real-Time ResultsSwift, AI-powered reporting to support clinical decisions
Prognostic ValuePredict outcomes based on molecular response trends
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