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    A Germline Test to Uncover Your Hereditary & Familial Cancer Risk

    OncoRisk® is a comprehensive, AI-powered hereditary cancer test designed to identify genetic mutations associated with more than 11 distinct hereditary and familial cancers. Built for both oncologists and patients, this test provides insights that enable early detection, informed decision-making, and proactive care planning for individuals and families at risk.

    Your Genetic Shield Against Hereditary Cancers

    Some cancers run in families. With a 74-gene panel covering the most relevant hereditary risk markers, OncoRisk® offers a science-backed way to uncover elevated risk across a broad spectrum of cancers—empowering clinicians and patients to take timely action with confidence.

    Covers 74 genes linked to 11+ hereditary and familial cancers

    Supports both affected patients and unaffected family members

    Enables informed surgical decisions (e.g. prophylactic mastectomy)

    Offers AI-powered reporting with personalized risk interpretation

    Includes pre- and post-test genetic counseling for patients

    Designed for actionable screening, prevention, and surveillance

    How It Works

    Genetic Sample Collection

    A simple blood sample is collected for germline DNA extraction.

    NGS-Based Germline Sequencing

    Our test uses deep sequencing of 74 high-priority cancer-related genes.

    AI-Powered Interpretation

    Reports are generated via the iCare™ platform and delivered with clear risk classifications and clinical action points.

    Genetic Counseling Support

    Patients receive guidance to interpret the report and discuss next steps.

    Applications

    For Clinicians & Oncology Teams

    • Identify hereditary risk in affected patients and their relatives

    • Initiate personalized screening and risk reduction plans

    • Guide decisions on prophylactic surgery and early surveillance

    For Individuals and Families

    • Understand inherited cancer risk and act early

    • Enable proactive health and lifestyle choices

    • Support family members in genetic risk assessment

    Why Choose OncoRisk®?

    • Broad panel covering risk across major hereditary and familial cancers
    • Actionable insights for real-world clinical decision-making
    • AI-enhanced reports with clear classifications and intervention paths
    • Backed by genetic counseling to support patients and families
    • Enables cascade testing across at-risk family members

    Key Actionable Genes

    Breast

    ATM, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, DICER1 , MLH1, MRE11, MSH2, MSH6, MUTYH, NBN, PALB2, PMS2, POLD1, POLE, PTEN, RADSO, RAD51C, RAD51D, SMARCA4, STK11, TP53

    Pancreas

    APC, ATM, BRCA1, BRCA2, BMPR1A, CDK4, CDKN2A, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, SMAD4, STK11, TP53

    Ovary

    ATM, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, EPCAM, MLH1, MSH2, MSH6, NBN, PALB2, PMS2, PTEN, RAD51C, RAD51D, TP53, STK11

    Renal

    BAP1,FH, FLCN,MET, PTEN, SDHA, SDHB, SDHC, SDHD, TSC1, TSC2, TP53, VHL

    Colorectal

    APC, BMPR1A, CDH1, CHEK2, EPCAM, GREM1, MLH1, MSH2, MSH6, MUTYH, PMS2, POLD1, POLE, PTEN, SMAD4, STK11, TP53, AXIN2, NTHL1, MSH3

    Skin

    BAP1, BRCA2, CDK4, CDKN2A, EPCAM, FH, FLCN, MLH1, MIFT, MSH2, MSH6, PMS2, PTEN, TERT,TP53

    Gastrointestinal

    APC, BMPR1A, CDH1, CTNNA1, EPCAM, MLH1, MSH2, MSH6, PMS2, SMAD4, STK11, TP53

    Endocrine

    MEN1, RET

    Prostate

    ATM, BRCA1, BRCA2, CHEK2, ЕРСАМ, HOXB13, MLH1, MSH2, MSH6, NBN, PALB2, PMS2, PTEN, RAD51D, TP53

    Lung

    EGFR, STK11

    1Cell.Ai
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