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    • ESMO 2024

    Therapy resistance detected in colorectal cancer by single circulating tumor cell genomics

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    Dr Gowhar S. (1Cell.Ai)

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    Highlights single circulating tumor cell (sCTC) genomic profiling in advanced colorectal cancer patients.

    Demonstrates detection of therapy-resistance signatures missed by conventional ctDNA analysis.

    Showcases mutation profiling linked to proliferative, stemness, and treatment-evasion pathways.

    Presents comparative analysis of sCTCs and paired ctDNA for improved cancer biomarker detection.

    Features genomic signatures associated with resistance mutations in colorectal cancer progression.

    Illustrates multi-omics insights supporting precision oncology and personalized treatment strategies.

    Emphasizes the value of live sCTC isolation for identifying tumor heterogeneity and actionable mutations.

    Supports liquid biopsy applications for therapy response monitoring and resistance prediction.

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    1Cell.Ai
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