Highlights comprehensive mutational profiling of single circulating tumor cells (sCTCs) in advanced pancreatic adenocarcinoma.
Demonstrates comparative genomic analysis between sCTCs and circulating tumor DNA (ctDNA).
Showcases detection of actionable mutations and pathogenic variants linked to pancreatic cancer progression.
Presents tumor heterogeneity analysis using mutation profiles, interaction patterns, and genomic signatures.
Features liquid biopsy insights showing mutations identified in sCTCs that may be missed in paired ctDNA.
Illustrates comparative analysis of SNVs, CNVs, splice variants, and mutation burden across sample types.
Supports precision oncology applications through non-invasive biomarker discovery and therapy resistance assessment.
Emphasizes single-cell genomic profiling for improved molecular characterization and personalized treatment strategies.