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    Advancing Single-Cell Precision

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    • Publications

    Precision Profiling of TP53 Alterations in Advanced Cancers: Real-World Evidence Linking Mutation Class to Genomic Instability and Co-occurring Actionable Drivers 

    Why TP53 Matters More Than We Thought  TP53 is the most frequently altered tumour suppressor gene in human cancer.  Yet for all its clinical relevance, our understanding of how different classes of TP53 mutations behave across different tumour types, at different disease stages; has remained incomplete....
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    • Featured
    • Publications

    Comprehensive Genomic Profiling Drives Precision Oncology and Expands Accessibility to Targeted Therapies in Uzbek Populations 

    Precision Oncology Must Be Global  At 1Cell.ai, we believe that the benefits of precision oncology should not be confined to patients in well-resourced healthcare systems. Cancer does not discriminate by geography and neither should access to advanced diagnostics. This study reflects that...
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    • Publications

    Integrative Genomic Analysis Reveals Pharmacogenomic Determinants of Chemotherapy Response 

    The Problem With One-Size-Fits-All Chemotherapy  Every oncologist knows the reality:-    Two patients with the same cancer diagnosis can respond very differently to the same chemotherapy regimen.   Some tolerate it well and respond powerfully. Others suffer severe toxicity with minimal benefit. The difference often...
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